Andrew A . Fischer , MD , PhD , Marta Imamura , MD , PhD , Hy Dubo , MD , FRCPC , Mark Young , M . D ., David A . Cassius , MD Contemporary pain management has shifted from symptom control to management based on the pathophysiological mechanisms of pain ( Woolf , 2004 ) . This has been associated with improvements in function and health-related quality of life as well as avoidance of therapeutic toxicity . One approach based on these principles , which will be discussed later in this chapter , is Segmental Neuromyotherapy . The clear understanding of the complex mechanisms involved in pain generation , modulation , amplification and perpetuation plays a critical role in a comprehensive pain control program . Recently , it has been recognized that constant and intense nociceptive sensory information generated by painful , inflamed deep somatic structures produce significant neurochemical and metabolic changes and reorganizations within corresponding spinal cord segments . These changes ...
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